Zofran Nausea Relief
Because nausea doesn't wait — and neither should relief.
When you're nauseated, swallowing a pill is often the last thing you can do — and waiting 45 minutes for it to absorb is the last thing you want. Zofran (ondansetron) works by blocking the serotonin receptors in your gut and brain that trigger the nausea signal. Delivered IM, it bypasses the digestive system entirely and gets to work in minutes — not after you've already been sick twice more.
Our Zofran booster delivers 4mg of ondansetron intramuscularly under medical supervision — the same medication used in hospitals for post-surgical nausea, chemotherapy side effects, and severe morning sickness. It's appropriate for stomach bugs, migraines with nausea, hangover-related nausea, motion sickness, and pregnancy symptoms. If you can't keep anything down, this is what works.
*Takes less than 5 minutes to administer
Minutes to administer<5
ONDANSETRON PER DOSE4mg
FASTER THAN ORAL ZOFRANmins
N-LOUNGE PRICE$29
Benefits of Zofran
Stops the nausea signal at the source
Ondansetron blocks 5-HT3 serotonin receptors in the gut wall and brain stem — the exact pathway your body uses to trigger the nausea and vomiting reflex.Works when oral medication can't
If you're vomiting, a pill isn't a realistic option. IM delivery bypasses your stomach entirely — no absorption required, no risk of vomiting it back up.Faster onset than oral Zofran
Oral ondansetron dissolves sublingually or in the gut — still faster than most antiemetics, but IM delivery compresses that window further, especially when every minute of nausea counts.Safe during pregnancy (with OB approval)
Ondansetron is one of the most widely used medications for hyperemesis gravidarum. Our team requires OB clearance before administering during pregnancy and will not administer in the first trimester without explicit physician approval.Stacks with IV hydration
Nausea almost always comes with dehydration. Zofran stops the nausea, then your body can actually absorb fluids again — which is why it pairs so well with our Stomach Bug, Morning Sickness, or After Party drips.
When to Boost
Stomach bug or viral nausea
When a stomach virus has you unable to keep anything down, Zofran IM stops the nausea signal so your body can start recovering. Pairs directly with our Stomach Bug drip to rehydrate and replace electrolytes at the same time.Morning sickness during pregnancy
Ondansetron is one of the most commonly prescribed medications for severe morning sickness. When you can't keep food or water down, IM delivery gets it in without asking your stomach to cooperate. Always consult your OB before treatment during pregnancy.Migraine with nausea
Nausea is one of the most debilitating parts of a migraine — and it also prevents you from keeping oral migraine medication down. Zofran IM stops the nausea and makes the rest of your treatment possible. Pairs well with Toradol and our Migraine Relief drip.Hangover nausea
Alcohol-induced nausea is a combination of dehydration, acetaldehyde buildup, and gastric irritation. Zofran controls the nausea signal while our After Party drip handles the hydration and nutrient replenishment side.Pre- or post-procedure nausea
Certain medications, anesthesia, and medical procedures commonly cause nausea. If you know you're prone to it, a Zofran shot before or after your procedure can prevent it from derailing your recovery.
Our formula
Zofran (Ondansetron)
4mg of ondansetron delivered IM — a serotonin 5-HT3 receptor antagonist that blocks the nausea signal at its source. The same medication hospitals use post-surgery and during chemotherapy. Prescription-grade, administered by licensed nursing staff.
Stop waiting to
feel normal again.
$29 in-lounge, administered by licensed nurses under medical supervision. Zofran pairs perfectly with our Stomach Bug drip, Morning Sickness drip, or After Party drip — stop the nausea and rehydrate at the same time. Pregnant patients require OB clearance before treatment.

